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Less means - more power. The high performance open source package for statistical data analysis and applied mathematics AtteStat is an add-in for desktop versions of the Microsoft Excel spreadsheets. Both 32-bit and 64-bit in one package. The combination of the unsurpassed convenience of spreadsheets and the effective interception of Microsoft Excel exceptions (frontend) and the maximum speed of the C++ programming language (backend). Winner of contest Microsoft Office Extensions (PC...

The wrapper allows to execute OpenCL code on CPU and GPU devices from VBA. Sources are available under https://github.com/Excel-lent/ClooWrapperVBA

WordMat is an add-on to Microsoft Word which creates a tab with math functionality. Part of the Math functionality is provided by other open-source applications like Maxima, GeoGebra, Graph and GnuPlot.

Excelsi-R is an Excel add-in that allows Excel spreadsheets to harness the power of the R statistical language by connecting to a running R process. R does not need to be installed on the computer running Excel, but it does require access to an R instance running Rserve (which can be on a remote computer). It supports incorporating R plots and graphs in an Excel workbook.

You may also like some newer work: http://createdatasol.com/ Project imDEV is an application of RExcel, which seamlessly integrates Excel and R for tasks focused on multivariate data visualization, exploration, and analysis. Interactive modules for dimensional reduction (imPCA), prediction (imPLS), feature selection, analysis of correlation (imCorrelations) and generation of networked structures (imGraph) provide an integrated environment for systems level analysis of multivariate data.