Showing 37 open source projects for "informatics"

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  • 1

    ntx

    Neutrality tests using the SNP site frequency spectrum

    Tests on "neutrality" are designed to detect systematic deviations from chance patterns in genetic data. This tool computes for a given SNP site frequency spectrum some standard test statistics like Tajima's D, Fay & Wu's H, etc. Additionally, the user may adapt the tests to specific demographies by specifying non-standard first and secondary moments. These can be obtained e.g. from simulations.
    Downloads: 0 This Week
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  • 2
    This software solves the Phylogeny problem using Median Networks. Exact and heuristic methods available. Input: an alignment and a reversible stepmatrix, output: (sub)optimal trees and their combinations. Steiner problem solver included.
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  • 3
    gsasnp2

    gsasnp2

    PubMed ID: 29562348 / DOI: 10.1093/nar/gky175

    * GSA-SNP2 is a successor of GSA-SNP (Nam et al. 2010, NAR web server issue). GSA-SNP2 accepts human GWAS summary data (rs numbers, p-values) or gene-wise p-values and outputs pathway genesets ‘enriched’ with genes associated with the given phenotype. It also provides both local and global protein interaction networks in the associated pathways. * Article: SYoon, HCTNguyen, YJYoo, JKim, BBaik, SKim, JKim, SKim, DNam, "Efficient pathway enrichment and network analysis of GWAS summary data...
    Downloads: 2 This Week
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  • 4
    PANDA-view

    PANDA-view

    An easy-to-use tool for data visualization and statistical analysis

    PANDA-view, an affiliated tool of PANDA, includes the methods for differentially expressed protein detection, missing value imputation and the parametric and non-parametric statistical tests. Meanwhile, the most commonly-used data visualization methods are also implemented in PANDA-view.
    Downloads: 4 This Week
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  • 5
    fcGENE: Genotype  format converter

    fcGENE: Genotype format converter

    Format converting tool for genotype Data (e.g.PLINK-MACH,MACH-PLINK)

    Main application is twofold: first to convert genotype SNP data into formats of different imputation tools like PLINK MACH, IMPUTE, BEAGLE and BIMBBAM, second to transform imputed data into different file formats like PLINK, HAPLOVIEW, EIGENSOFT and SNPTEST. Readable file formats: plink-pedigree (ped and map), plink-raw, plink-dosage, mach , minimac, impute, snptest, beagle and bimbam. Similarly all kinds of imputation of outputs are also accepted. Formats which can be generated by...
    Downloads: 2 This Week
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  • 6

    LightPCC

    Parallel pairwise correlation computation on Intel Xeon Phi clusters

    The first parallel and distributed library for pairwise correlation/dependence computation on Intel Xeon Phi clusters. This library is written in C++ template classes and achieves high speed by exploring the SIMD-instruction-level and thread-level parallelism within Xeon Phis as well as accelerator-level parallelism among multiple Xeon Phis. To facilitate balanced workload distribution, we have proposed a general framework for symmetric all-pairs computation by building provable bijective...
    Downloads: 1 This Week
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  • 7
    Community Detection Modularity Suite

    Community Detection Modularity Suite

    Suite of community detection algorithms based on Modularity

    - MixtureModel_v1r1: overlapping community algorithm [3], which includes novel partition density and fuzzy modularity metrics. - OpenMP versions of algorithms in [1] are available to download. - Main suite containing three community detection algorithms based on the Modularity measure containing: Geodesic and Random Walk edge Betweenness [1] and Spectral Modularity [2]. Collaborator: Theologos Kotsos. [1] M. Newman & M. Girvan, Physical Review, E 69 (026113), 2004. [2] M....
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  • 8

    runjags

    The 'runjags' R package and standalone JAGS extension module

    This package provides high-level interface utilities for MCMC models via Just Another Gibbs Sampler (JAGS), facilitating the use of parallel (or distributed) processors for multiple chains, automated control of convergence and sample length diagnostics, and evaluation of the performance of a model using drop-k validation or against simulated data. Template model specifications can be generated using a standard lme4-style formula interface to assist users less familiar with the BUGS syntax. A...
    Downloads: 1 This Week
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  • 9

    LightSpMV

    lightweight GPU-based sparse matrix-vector multiplication (SpMV)

    LightSpMV is a novel CUDA-compatible sparse matrix-vector multiplication (SpMv) algorithm using the standard compressed sparse row (CSR) storage format. We have evaluated LightSpMV using various sparse matrices and further compared it to the CSR-based SpMV subprograms in the state-of-the-art CUSP and cuSPARSE. Performance evaluation reveals that on a single Tesla K40c GPU, LightSpMV is superior to both CUSP and cuSPARSE, with a speedup of up to 2.60 and 2.63 over CUSP, and up to 1.93 and...
    Downloads: 0 This Week
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  • 10
    The General Hidden Markov Model Library (GHMM) is a C library with additional Python bindings implementing a wide range of types of Hidden Markov Models and algorithms: discrete, continous emissions, basic training, HMM clustering, HMM mixtures.
    Downloads: 5 This Week
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  • 11

    BiomeNet

    BAYESIAN INFERENCE OF METABOLIC DIVERGENCE AMONG MICROBIAL COMMUNITIES

    Metagenomics yields enormous numbers of microbial sequences that can be assigned a metabolic function. Using such data to infer community-level metabolic divergence is hindered by the lack of a suitable statistical framework. Here, we describe a novel hierarchical Bayesian model, called BiomeNet (Bayesian inference of metabolic networks), for inferring differential prevalence of metabolic networks among microbial communities. To infer the structure of community-level metabolic...
    Downloads: 0 This Week
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  • 12
    This is a project for Andre to share CellML related tools he works on that other people might find useful.
    Downloads: 2 This Week
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  • 13
    NSB entropy and mutual information estimator; applications to the analysis of neural code.
    Downloads: 1 This Week
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  • 14
    IDL specified API for manipulating and processing CellML 1.0 and 1.1. Includes C++ implementation. Accessible from a C++ program, or from any language for which a CORBA language mapping is available Also, a Java wrapper of the API is available.
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    Downloads: 11 This Week
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  • 15
    Downloads: 0 This Week
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  • 16

    metaopt

    Optimization toolbox for analyzing metabolic networks

    Metaopt contains direct C++ implementations of metabolic analysis methods based on flux optimization. It is mainly developed to solve thermodynamically constrained FBA and FVA (tFVA) efficiently.
    Downloads: 0 This Week
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  • 17
    parFE is fully-parallel high-performance finite element code targeted to the modeling of trabecular bones in humans. It employs scalable multigrid solvers for efficient solutions on massively parallel computers.
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  • 18
    EToS (Efficient Technology of Spike sorting; Extracellular recording To Spike trains) is an open-source system for spike sorting. EToS contains the programs of spike detection, feature extraction and clustering.
    Downloads: 0 This Week
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  • 19
    This software computes likelihoods for infinitely-many-sites sequence data under multiple merger coalescents. The likelihood can be computed exactly or approximated via importance sampling.
    Downloads: 0 This Week
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  • 20
    BIL++
    BIL++ is a set of standalone C++ packages for data processing in Bioinformatics (Graph mining, Bayesian networks, Genetic algorithm, Discretization, Gene expression data analysis, Hypothesis testing).
    Downloads: 0 This Week
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  • 21
    gfit creates an interface between computational models and experimental data and provides tools for their analysis
    Downloads: 1 This Week
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  • 22
    BigBang/Horizon is a proteomics data analysis pipeline with focus on the shotgun LC/MSMS workflow.
    Downloads: 0 This Week
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  • 23
    Stand-alone software tool for the interactive CE analysis of microarray data. The software is a user-friendly and allows on-the-fly study of CE
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  • 24
    An SQL handler to interface multiple databases data to the OpeNDAP Hyrax (BES) server. Written in C++, it uses unixODBC to query DB and can be dynamically extended to use proprietary ODBC API driver in many easy ways. It is bundled with scripts to ge
    Downloads: 0 This Week
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  • 25
    Sage Bionetworks
    Opensource software projects for genetics and genomics from Sage Bionetworks.
    Downloads: 0 This Week
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