Open Source R Machine Learning Software

OmicSelector is an environment, Docker-based web application, and R package for biomarker signature selection (feature selection) from high-throughput experiments and others. It was initially developed for miRNA-seq (small RNA, smRNA-seq; hence the name was miRNAselector), RNA-seq and qPCR, but can be applied for every problem where numeric features should be selected to counteract overfitting of the models. Using our tool, you can choose features, like miRNAs, with the most significant diagnostic potential (based on the results of miRNA-seq, for validation in qPCR experiments).

The caret (Classification And Regression Training) R package streamlines the process of building predictive machine learning models. It provides uniform interfaces for model training, tuning, evaluation, preprocessing, and variable importance. With support for over 200 models, caret is foundational for R workflows in modeling and machine learning.

R does not define a standardized interface for its machine-learning algorithms. Therefore, for any non-trivial experiments, you need to write lengthy, tedious, and error-prone wrappers to call the different algorithms and unify their respective output. {mlr} provides this infrastructure so that you can focus on your experiments! The framework provides supervised methods like classification, regression, and survival analysis along with their corresponding evaluation and optimization methods, as well as unsupervised methods like clustering. It is written in a way that you can extend it yourself or deviate from the implemented convenience methods and construct your own complex experiments or algorithms.

mlr3 is a modern, object-oriented R framework for machine learning. It provides core abstractions (tasks, learners, resamplings, measures, pipelines) implemented using R6 classes, enabling extensible, composable machine learning workflows. It focuses on clean design, scalability (large datasets), and integration into the wider R ecosystem via extension packages. Users can do classification, regression, survival analysis, clustering, hyperparameter tuning, benchmarking etc., often via companion packages.