ScriptBot is a scriptable IRC bot. Based on PircBot and BSF, it allows to fully customize the bot's behaviour by editing script files in the scripting language of your choice.
The PHP:IRC suite allows you to run an IRC applet on your site, an IRC "bot" similar to eggdrop, and to administer them as well as CGI:IRC. PHP:IRC is compatible with CGI:IRC, phpBB, YaBB, and other communities.
JackBot is an IRC bot written in 100% Java. It provides a flexible, extensible plugin architecture and a rich scripting environment built upon the Rhino JavaScript engine.