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OfficeSIP Softphone and Messenger are two enterprise VoIP SIP clients written in C# in .NETFramework. The SIP clients make use of Microsoft UCC API SDK, ensuring the highest quality of audio and video. Compatible with Office Communications Server.
See also open source, cross-platform:
1) simple messenger Brief Msg at http://briefmsg.org
2) MUVConf is a multi-user video conferencing, see demo video http://youtu.be/YrBU-Aqtvrk, download https://code.google.com/p/muvconf/downloads/list
Kill Skype Home gets rid of the Skype Home window that automatically pops up when Skype starts. It also includes features designed to make the Skype experience better for the minimalist at heart.
GibPhone is a highly extensible VoIP/IM client for the .NETframework that uses a powerful plugin engine to allow for UI extensions and any call control stack / media payload / transport protocol combination.
Cabal is a C++ framework that provides support for high prestation parallel processing network servers and clients. It doesn't provide a protocol, it just gives you the abstraction of data sending/receiving in real time or priority scheduling.