Search Results for "caller"

Often times, the production system network is inaccessible from the local development environment. If issues are encountered in production systems, it is impossible to use IDEs to debug the application remotely. More importantly, debugging in production environment is unacceptable, as it will suspend all the threads, resulting in the suspension of business services. Developers could always try to reproduce the same issue on the test/staging environment. However, this is tricky as some issues...

...Kim S et al, "Virmid: accurate detection of somatic mutations with sample impurity inference", Genome Biology 2013, 14:R90 http://genomebiology.com/2013/14/8/R90/abstract Virmid (Virtual Microdissection for SNP calling) is a Java based variant caller designed for disease-control matched samples. Virmid is also specialized for identifying potential within individual contamination where the disease sample cannot be purified enough. While the SNP calling rate is severely compromised with this heterogeneity, Virmid can uncover SNPs with low allele frequency by considering the level of contamination (alpha). ...

SIPeS - Site Identification from Paired-end Sequencing