SimpleITK
A layer built on top of the Insight Toolkit (ITK)
... be applicable to SimpleITK. Unlike ITK's support of n-dimensional spatio-temporal images, SimpleITK supports 2D, 3D and 4D images. The dimensionality refers to spatiotemporal dimensions, the voxels can be n-dimensional vectors. Open-source multi-dimensional image analysis in Python, R, Java, C#, Lua, Ruby, TCL and C++. Developed by the Insight Toolkit community for the biomedical sciences and beyond.