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...It also features a number of standard processing algorithms for smoothing, thresholding, masking etc. images and models, both with graphical user interfaces and/or via the command-line. See our YouTube channel for tutorial videos via the homepage. The applications are all built out of a uniform user-interface framework that provides a very high level (Qt) interface to powerful image processing and scientific visualisation algorithms from the Insight Toolkit (ITK) and Visualisation Toolkit (VTK). The framework allows one to build stand-alone medical imaging applications quickly and easily.

Gimp Gradient Extrapolate is a plugin for Gimp 2.8. It fills gaps or removes objects, both of which are surrounded by a gradient like smooth image structure (e.g. sky). Refer to the wiki to see how to use it. Note, since this plug-in is written in python and involves optimization problems and non-filter operations, this script's runtime can be rather long, depending on the size of your image selection. Consider donating to this project: https://sourceforge.net/projects/gimp-g-e/donate