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XMIPP is an image processing suite for 3D-reconstruction of biological specimens from transmission electron microscopy data. NOTE that stable releases (including binaries) are longer stored at Sourceforge, but are available at http://xmipp.cnb.csic.es
Open Source Remote Sensing OSSIM project, pronounced "awesome", will leverage existing algorithms/tools/packages from the open source community in construction of the ultimate Remote Sensing/Image Processing/GIS package. osgPlanet extends OSSIM and Op
OpenVL is a framework for handling, processing & visualizing volumetric data (CT, MRI etc). It provides: powerful data access & layout API, plugins for volume processing tasks (image processing, segmentation etc), and support for multiple file-formats.