pywebview
Build GUI for your Python program with JavaScript, HTML, and CSS
...You can use pywebview either with a lightweight web framework like Flask or Bottle or on its own with a two way bridge between Python and DOM. pywebview uses native GUI for creating a web component window: WinForms on Windows, Cocoa on macOS and QT or GTK on Linux. If you choose to freeze your application, pywebview does not bundle a heavy GUI toolkit or web renderer with it keeping the executable size small. pywebview is compatible with Python 3.