TurboGears is a hybrid web framework able to act both as a Full Stack framework or as a Microframework. TurboGears helps you get going fast and gets out of your way when you want it! TurboGears can be used both as a full stack framework or as a microframework in single-file mode. TurboGears 2 is built on top of the experience of several next-generation web frameworks including TurboGears 1 (of course), Django, and Rails. All of these frameworks had limitations that frustrated us, and TG2 was...
Pyjamas-Desktop is the Desktop version of the Pyjamas WebWidget toolkit. Pyjamas-Desktop can even execute javascript, and embed plugins such as Flash. Pyjamas-Desktop is now part of http://pyjs.org
TurboGears widget plugins' source repository. If you made a TurboGears widget, mail me to get permission to put your TurboGears widget here. Download TurboGears widgets from http://www.turbogears.org/cogbin/
yuik is an abstract widget library for creating GUIs. The actual frontend can be chosen at runtime which allows the program to run under Tk, as a shell program, and even as a web-application. More frontends like an irc-bot, wxWidgets, or XUL are planned.