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This project is a complete cross-platform (Windows, Linux) framework for Evolutionary Computation in pure python. See the project site at http://pyevolve.sourceforge.net or the blog at http://pyevolve.sourceforge.net/wordpress
BS Eagle Project is an open source black-oil simulator. The goal of this project is to provide a free access to the modern oil simulator to study new methods of simulation. The project has a modular architecture and open to modifications and extensions.
vhdPLUS Development Framework is a modern, fully component oriented simulation engine and middleware solution created by and reflecting many years of the R&D experience of both the MIRALab, University of Geneva and VRlab, EPFL labs in the domain of VR/AR
The Open Distributed Framework project is aimed at developing an open-source, cross-platform framework for distributed, high-performance physical modelling and simulation.
mgE3D - mgEngine3D is an unfinished 3D Engine based on OpenGL. By now
it provided several features like scenetree, mesh/skeleton mesh rendering and animation, terrain, materials, textures, multiple viewports, Python exporter for Blender and so on.