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An environment (library + IDE) that emulates Delphi but uses python as the programming language and wxPython as the graphical API. Starting with the library, we have a set of modules/classes that emulates the units/classes of the famous VCL.
TurboGears 2 is a web framework, but unlike some of its competitors, it's not a monolithic unit, it's a collection of libraries, WSGI components, and web development tools that works well together and is configured to provide a great out of the box.
The PyQt4D (Python Qt for Designer) is an Open Source Project making Qt Designer full-featured RAD (Rapid Application Development) tool to develop data-aware two- or multi-tier applications using Python language and Qt library.
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A Graphical Editing Framework(GEF), for Python. It provides a canvas similar to wxArt2D and a editing framework based on MVC. The framework can be used to develop scientific and engineering tools that require graphical editing.
Leilany is a framework to build GUI applications with Python and GTK, using de MVC pattern design. Interested in build the gadgets for invoicing and the necessary requirements. The main goal is make applications with low memory.
Drupy is a Python implementation of the Drupal content management system. This project is no longer maintained. You can find the original codebase at https://github.com/brendoncrawford/drupy/
Eynhorn is a 3d action rpg engine / framework. It will support dialog system, fight system, armors and weapons, and will include a map assembly. It is realized in Soya 3d and Python, so it'll be platform independent.