Maestro Framework is a Python framework for orchestrating AI subagents across complex tasks. It breaks a user objective into smaller subtasks, assigns those subtasks to worker models, and refines the results into a final output. The original workflow used Claude Opus and Haiku, while newer variants support Claude 3.5 Sonnet, GPT models, Gemini, Cohere, Groq, LM Studio, and Ollama through different scripts and LiteLLM support.