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The mendelson OFTP2 is a JAVA-based open source OFTP2 solution. It contains a logging- and configuration UI and supports encryption, digital signatures, message compression, TLS, certificate exchange, message routing, mail notification
C library for sending e-mail (with attachments) from C/C++
C library intended to give C/C++ developers a quick and easy way to send e-mail from their applications. Supports multiple To/Cc/Bcc recipients and multiple attachments without size limitation. For the actual SMTP communication either libcurl can be used or the built in SMTP support. The library can also be used to just create a multipart MIME message body.
Also comes with a command line application (quickmail) for sending mails (mutiple attachments supported) from command line or scripts.
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AS2Secure is a PHP Lib to allow you to send and receive AS2 message from partners. Based on OpenSSL, documents are SIGNED and CRYPTED to build SMIME messages ready to be sent over HTTP connection.