Acqlite is Gnutella file sharing program based on LimeWire, Acquisition and Cabos. It is free software, no spyware, no adware. It provides simple interface, multi languages support, and iTunes + iPod integration.
MultiDC++ aims to be a DC++ port with support for many different operating systems. In addition, it runs as a server enabling you to interface with it locally or remotely using several user interfaces.
Shakespeer is a Direct Connect implementation for Unix-like systems. It aims to be fast, easy to use and compatible with DC++. The major goal of ShakesPeer is to create a Mac OS X application with an Aqua graphical userinterface.
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A port of DC++ to Mac OS X with a userinterface according to the Apple Human Interface Guidelines. Because this client is built on DC++ it is compatible with the Windows version and the Macintosh version will benefit from future updates of DC++.
BlastServ is a plugin used with XChat and Mac OS X. It will be an IRC File Server (FServ or FServe), similar to SysReset for Windows or Obsidian. Fservs send files over DCC, and have an interface like FTP. They are a quick and easy way to transfer files.
OpenAG is the first Unix/Linux/Mac OS X implementation of the (unofficial) Audiogalaxy File Sharing Protocol. OpenAG includes both client and server projects. The client is available as a command line application or with a Mac OS X Aqua interface.