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CardioBox is a plug-and-play tele-ECG platform that uses a regular electronic mailbox and its protocols to support the core of the telemedicine information system and associated data procedures. Using an Internet service instead of a server-based infrastructure means that no expertise is required to setup a telemedicine central, furthermore allowing your work group the freedom to work from any place. Upgrading your working experience doesn't mean you have to invest a lot of financial resources: the CardioBox platform is free and you only pay per use. End-users, namely the technicians responsible for the acquisition of ECG, are provided with a simple application to upload the procedures into the email centre.