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Dia Diagram Editor is free Open Source drawing software for Windows, Mac OS X and Linux. Dia supports more than 30 different diagram types like flowcharts, network diagrams, database models. More than a thousand readymade objects help to draw professional diagrams. Dia can read and write a number of different raster and vector image formats. Software developers and database specialists can use Dia as a CASE tool to generate code skeletons from their drawings.

dedalo is a 2d cad drawing software written in python3. It is licensed under the GPLv3. Dedalo features: layers, snaps (endpoint, intersection, midpoint), line, polyline, rectangle, delete, polygon, rectangle, arc, circle, points, text, spline, freehand drawing. Move, scale, rotate, offset, cut, extend, hatch, dimension, copy. English, italian languages SVG read-write. Not all features all fully supported. For more information a user manual is provided(pdf format, italian).

A drawing program for chemical structure formulas, in the vein of chemtool, BKChem, EasyChem, or Xdrawchem.

Skencil is a vector drawing program. It's written almost completely in python for flexibilty with some modules written in C for speed.