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The Systems Biology Workbench(SBW) is a framework for application intercommunications. It uses a broker-based, distributed, message-passing architecture, supports many languages including Java, C++, Perl & Python, and runs under Linux,OSX & Win32. It comes with a large number of modules, encompassing the whole modeling cycle: creating computational models, simulating and analyzing them, visualizing the information, in order to improve the models.

JPPF makes it easy to parallelize computationally intensive tasks and execute them on a Grid.

Web Objects in XML (Framework) is an interoperable and lightweight system for distributed objects. It is currently built in Java and C#. Remote objects are serialized in a standard XML format, and they are accessible trough their own URL.