Pyjamas-Desktop is the Desktop version of the Pyjamas Web Widget toolkit. Pyjamas-Desktop can even execute javascript, and embed plugins such as Flash. Pyjamas-Desktop is now part of http://pyjs.org
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Filescape is a file manager for any GNU/Linux Operating System. It is written in Python and uses the GTK+ toolkit. Filescape aims to combine the best features of Nautilus, pcmanfm, and Thunar.
PylotLight is a cross-platform productivity boosting application. It supports plugins written in python that can customize and extend its functionality.
Collection of widgets, gadgets and desklets for different Linux and Windows based widget engines (such as Firefox, Opera, SuperKaramba, Screenlets, gDesklets).
Powersave Applet consists of a script, that does various tips and tricks from Intel's PowerTop and lesswatts.org to reduce power consumption while your laptop is on battery. There is also an applet that provides a nice status icon in Gnome or KDE.
GeoXPlanet is a program that integrates geolocation technology and xplanet. View the earth, with a geographic plot of the computers you've connected to, directly on your desktop background in near real-time. As of 0.4.5, a SQLite format MaxMind GeoLiteC
Vierstein (FourStone) is a RPG creation and playing kit based upon games like Unlimited Adventures. It uses a custom, and hopefully inventive, rule-set that focuses on single player environment. Built upon Python and Pyui.
Infectors it's a puzzle game inspired in frozen fruits and boxworld games. You must save the earth from a infectors virus epidemic, trapping all bugs in antiviral cryogenic capsules. It comes with a level editor
A simple Gedit Plugin which enables a markup syntax to produce extended characters. 59 defaults but extra character support can be added easily making this plugin highly configurable.
A Del.icio.us add-on Python script to search links in exported bookmark files. Instead of using public overloaded del.icio.us servers to find and retrieve your links, use yummy and let it search your exported delicious bookmark files locally much faster.
Remote control a Windows machine without bluetooth using a java (j2me) mobile device. Either use a direct intenet connection, or a bluetooth-net proxy server (resolving bluetooth/802.11g interference while streaming).
PyPassMan is a password manager that allows user to store passwords and password-related informations. It uses a strong cryptographic library to ensure information security. Its aim is to organize those informations in a simple and efficient way.
A document/data/information management system that does not require anything other than a base Python installation (ie., with no dependencies), this application is aimed towards creating a full-featured easy-to-use platform-independent manager.
Python / GTK / GNOME applet for wireless configuration, similar to WindowsXP "Zeroconf" wireless. Shows network status, available access points, and allows the user to connect to a specific AP. Stores WEP keys and handles DHCP.
PythoPhotoPod is a Python-based GTK+ GUI for Linux synchronizing photos and photo albums with your iPod Photo (tm) (also known as iPod with a color display), iPod Video (tm) or iPod Nano (tm).