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Generating Excel 97+ files with Python 2.4+ (need decorators), importing Excel 95+ files, support for UNICODE in Excel files, using variety of formatting features and printing options, Excel files and OLE2 compound files dumper. No need in Windows/COM
pyXLWriter is a Python library for generating Excel compatible spreadsheets. It's a port of John McNamara's Perl Spreadsheet::WriteExcel 1.0 module (see http://www.cpan.org) to Python. Requires Python 2.1+. [Project was stopped]