...Its multi-pane interface synchronizes multiple orthogonal views with a central 3D viewport, making it ideal for analyzing complex brain imaging data such as connectomics datasets. Neuroglancer operates entirely client-side, fetching data over HTTP in a variety of supported formats including Neuroglancer precomputed, N5, Zarr, and NIfTI, among others. The viewer is built with a multi-threaded architecture, separating rendering and data processing to ensure smooth performance even with massive datasets. Extensively used in neuroscience research, Neuroglancer supports integration with tools.