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nichenetr: the R implementation of the NicheNet method. The goal of NicheNet is to study intercellular communication from a computational perspective. NicheNet uses human or mouse gene expression data of interacting cells as input and combines this with a prior model that integrates existing knowledge on ligand-to-target signaling paths. This allows to predict ligand-receptor interactions that might drive gene expression changes in cells of interest. This model of prior information on...

This part of the book teaches you how to leverage the plotly R package to create a variety of interactive graphics. There are two main ways to creating a plotly object: either by transforming a ggplot2 object (via ggplotly()) into a plotly object or by directly initializing a plotly object with plot_ly()/plot_geo()/plot_mapbox(). Both approaches have somewhat complementary strengths and weaknesses, so it can pay off to learn both approaches. Moreover, both approaches are an implementation of the Grammar of Graphics and both are powered by the JavaScript graphing library plotly.js, so many of the same concepts and tools that you learn for one interface can be reused in the other. ...