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optPBN

An optimization toolbox for probabilistic Boolean networks

We introduce optPBN, a Matlab-based toolbox for the optimization of probabilistic Boolean networks (PBN) which operates under the framework of the BN/PBN toolbox from Shmulevich et al. optPBN offers an easy generation of probabilistic Boolean networks from Boolean rule-based modeling and allows for flexible measurement data integration from multiple experiments and a subsequent integrated optimization problem generation which then can be solved with different optimizers. Thereby optPBN allows for the identification of Boolean functions in the model from a given set of candidate Boolean rules which can be applied for network inference study. ...

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Last Update: 2015-09-24
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