Numba is an open source JIT compiler that translates a subset of Python and NumPy code into fast machine code. Numba translates Python functions to optimized machine code at runtime using the industry-standard LLVM compiler library. Numba-compiled numerical algorithms in Python can approach the speeds of C or FORTRAN. You don't need to replace the Python interpreter, run a separate compilation step, or even have a C/C++ compiler installed.
Cython is an optimizing static compiler for both the Python programming language and the extended Cython programming language (based on Pyrex). It makes writing C extensions for Python as easy as Python itself. Write Python code that calls back and forth from and to C or C++ code natively at any point. Easily tune readable Python code into plain C performance by adding static type declarations, also in Python syntax.