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Pygone is to be a programming language built on top of Python, aimed to be a ridiculously high level programming language, allowing for it to be used to introduce people to programming.
Fusion is a powerful high level programming language that merges several feature from Ruby, Python, Java, C++, Visual Basic, etc, in a only language. It's implemented by means of a compiler written in Haskell that generates Ruby code.
UfakPython is a small subset of Python programming language, for small embedded devices, like PICs. UfakPython sources are translated to C by UfakPython Compiler. Small Device C Compiler can then compile the C outputs to the target device's codes.
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Delight is an imperative, object-oriented programming language with a Python-like syntax. Internally, it is based on the D programming language, and therefore supports classes, interfaces and templates, and compiles to efficient native code using GDC.
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f2cpp is a python script to convert Fortran 77 to C++ code. The output files of f2cpp script, in contrast to the well-known f2c translator, can be easy read by human.
A disassembler for the linux platform. Currently this supports x86 ELF files assumed to be written in C and output to intel- syntax assembly language; however the design is modular and replacements for any of these can be written.
Psyco showed that it is possible to execute Python code at speeds approaching that of fully compiled languages, by "specialization".
The project is now dead and replaced by PyPy: http://pypy.org/
STDL (Structured test description language) is a domain-specific testing language that is used to auto-generate unit test code. It supports a myriad of output languages (incl. C#). The project's aim is that of reducing the resources required for testing
IDC is an interactive decompiler, where the user starts with an almost literal translation of Assembly code in C language, which he progressively decompiles by the successive application of low-level refactorings, ultimately leading to high-level C code.
Pyston is a GEM based plugin for GCC that traverses the C/C++ source code
and automagically writes thin, fast Python wrappers for all types and functions. These wrappers once created, are independent of the tool and can be directly distributed.
A script(ing/ed/able) optimizing compiler for the C and Objective-C languages (and in the future other languages such as C++, D and Java). Written in a scripting language to allow for experimentation with code generation and optimization techniques.
The Markovski project implements an interpreter/compiler for a language named Markovski, used to write Markov algorithms (see http://en.wikipedia.org/wiki/Markov_algorithm).
UIMP(Unified Image Manipulation Program) is an OS independent Image Processing system, which provides over 1000 algorithms and supports web online, console and GUI program.
PYthon to ASsembler TRAnslator. At this moment supports Microchip PIC16 instruction set only. Its main goals are: to support a wide range of microcontrollers and processors, to generate compact and effective code.
Decompyle is a python disassembler and decompiler which converts Python byte-code (.pyc or .pyo) back into equivalent Pythonsource. Verification of the produced code (re-compiled) is avaliable as well.