Shakespeer is a Direct Connect implementation for Unix-like systems. It aims to be fast, easy to use and compatible with DC++. The major goal of ShakesPeer is to create a Mac OS X application with an Aqua graphical user interface.
HXD for OS X is a complete distribution of HXD for Mac OS X. It includes a preferences pane for the System Preferences application for controlling the server.
BitRocket is a Native BitTorrent client for Mac OS X. At the heart of it's core resides the powerful libtorrent BitTorrent library. BitRocket is aimed to be a good alternative to other Mac OS X BitTorrent clients.
OpenAG is the first Unix/Linux/Mac OS X implementation of the (unofficial) Audiogalaxy File Sharing Protocol. OpenAG includes both client and server projects. The client is available as a command line application or with a Mac OS X Aqua interface.
dcosx is a Direct Connect client based on dclib. It takes full advantage of Mac OS X's Cocoa environment, so we x'rs don't have to trudge through QT.
Cocoa Bittorrent client and C torrent library - based on fork of libbt, with high performance and compatibility, advanced prioritisation and scheduling, DHT, and Protocol Encryption.
ithunder is download utility for Mac OS X based on axel and other libs.