Aeru IRC is IRC Client for the .NET Framework. It made with C# programming language and features a full Graphical Interface. Aeru IRC uses XML to store servers and channels and app settings. The GUI uses the power of .NET.
IRC Services for the Unreal IRC server, written in C#, with a Microsoft SQL Server backend. Files are stored in XML. Services include NickServ, ChanServ, MemoServ, BotServ, HostServ, and OperServ.
An easy-to-use .NET IRC client for Windows, written in C#.
Flex Chat is an Open Source IRC client, which is written in C#. It is comfortable, easy to use and configure client, which is supporting VB, Perl, PHP, Tcl, C#, C++ scripts and XML database.
A Release bot written in C# and fully compatible with Microsoft.NET and Mono. Monitors RSS feeds for new releases (Software, News etc).
SharpBot is a multi-protocol bot that supports multiple protocols (such as OSCAR, IRC, and Jabber). The bot's functionality may be extended by external modules such as scripting modules, plugin modules, and protocol modules.
Smirk is a very user-friendly C# IRC client that uses the SmartIrc4net component.