Search Results for "genome"

ClustAGE is a command-line tool built using the Perl scripting language for the purpose of analyzing and comparing accessory genomic elements (AGEs) between genomes. It takes as input sets of AGE nucleotide sequences previously identified from the genome sequences of two or more separate organisms. These AGE sequence sets can be extracted from complete or draft whole-genome nucleotide sequences using the previously-developed software tools Spine (https://github.com/egonozer/Spine) and AGEnt (https://github.com/egonozer/AGEnt). See README (https://sourceforge.net/p/clustage/code/ci/master/tree/README.md) for more information.

...Please refer to: https://github.com/suhrig/pingpongpro Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs, predominantly active in the germ line. There, they limit the detrimental effect of transposons on the genome. They do so by forming a complex with Piwi proteins. The complex binds and then cleaves mRNA molecules of active transposons. The resulting mRNA fragments induce the production of more piRNAs, thus reinforcing the anti-transposon response in a feed-forward loop called the "ping-pong cycle". A key question in ping-pong cycle research is identification of piRNAs which are amplified through the cycle. ...

...It is oriented mainly towards targeted resequencing experiments, with a set of functions for general purposes. BCP also includes a function for breast cancer risk estimation, based on the Gail model, using both clinical and genome data.