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...The latest stand-alone version can be downloaded at http://bit.ly/IBEX_MDAnderson The latest source-code version can be downloaded at http://bit.ly/IBEXSrc_MDAnderson IBEX (imaging biomarker explorer) is an open infrastructure software platform that flexibly supports common radiomics workflow tasks such as multimodality image data import and review, development of feature extraction algorithms, model validation, and consistent data sharing among multiple institutions. IBEX software package was developed using the MATLAB and C/C++ programming languages. The software architecture deploys the modern model-view-controller, unit testing, and function handle programming concepts to isolate each quantitative imaging analysis task, to validate if their relevant data and algorithms are fit for use, and to plug in new modules.