Search Results for "rna analysis"

The software package 'relax' is designed for the study of molecular dynamics through the analysis of experimental NMR data. Organic molecules, proteins, RNA, DNA, sugars, and other biomolecules are all supported. It supports exponential curve fitting for the calculation of the R1 and R2 relaxation rates, calculation of the NOE, reduced spectral density mapping, the Lipari and Szabo model-free analysis, study of domain motions via the N-state model and frame order dynamics theories using anisotropic NMR parameters such as RDCs and PCSs, the investigation of stereochemistry in dynamic ensembles, and the analysis of relaxation dispersion data.

corona is an exploratory bioinformatics project that applies reverse-engineering ideas to SARS-CoV-2. It treats biological information processing as an analogy to software analysis to help explain the viral genome from first principles. Python scripts download genomic sequences from GenBank and translate RNA into amino-acid chains. The project identifies and annotates proteins encoded by the genome. It also experiments with OpenMM for molecular simulation and protein-folding work. Supporting data, protein resources, vaccine-related material, research questions, and analysis notes make the repository a hands-on workspace for studying viral structure and genetics.

COV2HTML provides an easy and 'in home' web interface for biologists that allows coverage visualization of the NGS alignment needed for the analysis. It combines two essential processes: (i) MAP2COV, a tool that converts the huge NGS mapping or coverage files into light specific coverage files which contains genetic elements informations. (ii) COV2HTML, a visualization interface allowing a real-time analysis of data with selected criteria. Thus this interface offers a visualization of NGS mapping coverage data (DNA-seq, RNA-seq, ChIP-seq and TSS) performed in different prokaryotic organisms (bacteria, viruses...) or different experimental conditions (mutant versus wild type strains or different growth states…) facilitating studies.