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Gnupylot is a GUI for gnuplot (the widely used multi-OS plotting utility). It's written in Python using PyQt4 libraries. With Gnupylot you can save your plots (even the datasets). It's still in Alpha stage.
Snidget is a python program which tracks your financial information, in particular your expenses and income. The user adds each transaction on their accounts and snidget can provide reports about how much you're spending. Includes both CLI and GUI.
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--UPDATE-- New Version is now integrated in the official PyMOL plugin repository! --UPDATE--
The BNI (Beyond Normal Interaction)- Tools is a plug in for the PyMOL molecular visualization system which adds additional functionalities and presets to the PyMOL GUI and also adds useful extended commands.
pyPdf-GUI is a Python-based graphical user interface for the pure-Python PDF library pyPdf, allowing the user to easily manipulate PDF files. It can extract pages, merge several files into a single one, rotate pages in a file, extract text, etc.
This money manager is a simple one (very simple at that) and someday might fork and have a GUI counterpart. Note: you need python installed on your system for this to work.
A small note taking program for the terminal. Tnote aims to be a small, quick and easy to use note taking app for the terminal similar to sticky style gui note taking apps such as Tomboy notes.
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PyOrganizer is a cross-platform (Python/GTK) personal organizer, with a GUI optimized for the Nokia Internet Tablets (n810, n800, and n700). The financial/budgeting features are now operational, and rudimentary mileage tracking has just been added.
The LDS Administrative Tools Project provides tools to aid in the administration of ward or branch leadership. Current tools are text-based, but a GUI toolset is under development. (keywords: clerk, secretary, membership, records, assistant, report)
FLAG was designed to simplify the process of log file analysis and forensic investigations. FLAG facilitates efficient analysis of large quantities of data within an interactive environment. PyFlag is the reimplementation of FLAG in Python.
PyMaTi is a simple and easy to use GUI for numerical and scientific computing in Python. It surrounds well know packages NumPy and Matplotlib and provides possibility to immediately play with numerical python from intuitive user interface.
This is a GUI for pyPDF. It allows the user to select a list of pdf's and it "glues" the pdf files together into one pdf file. It was developed with python/glade/gtk. A deb and rpm package are both available. Let me know if you would like to help.
PyPlotSuite aims to provide immediate, easy-to-use, GUI tools to display, analyze and create publication-quality 2D plots of 1D data series, images, 2D arrays. This project is based on (and would not exist without) pygtk, matplotlib and numpy.
A python package which aids in the analysis of ViEWER (http://www.webpages.uidaho.edu/~bdyre/viewer.htm) epoch logs. A wxPython GUI helps the user build a python script which uses the package to perform timeseries and spectral analyses.
QME-DEV Workbench (wxScipy) is a data analysis workbench based on Python, SciPy, Numpy and MatPlotLib(PyLab) and uses wxPython for the GUI. It can be used for non-linear analysis with a large set of experimental or generated data. Load/Acquire / Save/ Gr
N-Ctrl Work Log Manager tracks time invested in your projects, producing daily, weekly or custom reports. Supports standard as well as 9/80 ("split-Friday") work weeks. Intuitive, flexible GUI and command line clients with Nokia 770 support.
Simple OS X "droplet" for quick data visualization. Drag-and-drop one or more text files containing series data and a simple scatter plot is generated containing each series with different symbols, legend, etc. GUI-less alternative to gnome PlotDrop.
OpenSessame is a personnel entry control and time tracking management system. Platform independent, multi-node, client-server system, written in Python, with wxPython/wxWidgets client, a web management gui and PostgreSQL database backend.