fitGCP
Fitting genome coverage distributions with mixture models
...fitGCP is a framework for fitting mixtures of probability distributions to genome coverage profiles. Besides commonly used distributions, fitGCP uses distributions tailored to account for
common artifacts. The mixture models are iteratively fitted based on the Expectation-Maximization algorithm.
Please find the accompanying paper here:
http://dx.doi.org/10.1093/bioinformatics/btt147