Showing 435 open source projects for "python"

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  • 1

    iMir

    Integrated pipeline for HT miRNA-Seq data analysis

    Processing of smallRNA-Seq data to gather biologically relevant information requires application of multiple statistical and bioinformatics tools from different sources, each focusing on a specific step of the analysis pipeline. The analytical workflow can be challenging for the continuous interventions by the operator, a critical factor when large numbers of datasets need to be analyzed at once. To allow a flexible and comprehensive analysis of smallRNA-Seq data we designed a novel modular...
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  • 2

    InMethyl

    Design of target-specific primers for bis. sequencing of CpG-islands

    InMethyl is a Python-based application for the design of target-specific primer combinations for PCR amplification and bisulfite sequencing of complete CpG-islands. InMethyl uses bowtie high-throughoutput aligner to identify potential mis-priming sites in the bisulfite treated or intact genome and then – undesirable potential PCR products. InMethyl provides a balance between various characteristics that allows to pick up primers in hard-to-study genomic regions.
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  • 3

    UniPyRange

    Tool to fetch protein/DNA truncation constructs from Uniprot DB

    Very simple python script which saves you the pains of counting the amino acids/DNA bases in fasta files from the Uniprot and NCBI RefSeq Database (1, 2). Lets say you want the amino acid sequence of range 128-387 from a 1000 amino acid protein - this script will help you to avoid counting mistakes by just showing you the specified sequence in amino acids and coding DNA base pairs (ideal for amplification primer design) of a specified Uniprot ID
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  • 4
    ILNumerics.Net
    math lib for .NET. n-dim arrays, complex numbers, linear algebra, FFT, sorting, cells- and logical arrays as well as 3D plotting classes help developing algorithms on every platform supporting .NET. Sources from SVN, binaries: http://ilnumerics.net
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  • 5
    Project now hosted at GitHub: https://github.com/djparente/coevol-utils
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  • 6

    LipidWrapper

    Create lipid-bilayer models of arbitrary geometry.

    LATEST VERSION NOW LOCATED AT http://git.durrantlab.com/jdurrant/lipidwrapper As ever larger and more complex biological systems are modeled in silico, approximating physiological lipid bilayers with simple planar models becomes increasingly unrealistic. When building large-scale models of whole subcellular environments, models of lipid membranes with carefully considered, biologically relevant curvature are essential. LipidWrapper, written by Jacob Durrant in the lab of Rommie E. Amaro,...
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  • 7
    This script can convert raw diffraction images to JPEG files. Support ADSC, MarCCD, Mar345, RAXIS and PILATUS, and can be run on Windows, Linux and Mac OS X.
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  • 8
    ADTEx

    ADTEx

    Aberration detection in tumour exome

    Aberration Detection in Tumour Exome (ADTEx) is a tool for copy number variation (CNV) detection for whole-exome data from paired tumour/matched normal samples.
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  • 9

    FingerID

    Metabolite identification via machine learning.

    [NOTICE!] FingerID since version 1.4 will be hosted on github: https://github.com/icdishb/fingerid A metabolite identification software using tandem mass spectrometry and kernel methods. The related paper can be found at http://bioinformatics.oxfordjournals.org/content/early/2012/07/18/bioinformatics.bts437.abstract. Now it supports unix/linux like system.
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  • 10
    Ymap - Yeast Mapping Analysis Pipeline

    Ymap - Yeast Mapping Analysis Pipeline

    Pipeline for large-scale genome changes analysis of genome datasets.

    The active use repository has migrated over to: https://github.com/darrenabbey/ymap The repository here was errantly created with some large binary files included. Attempts to extract the files from the history here have failed. A copy of the history was successfully scrubbed and then hosted at github. -------- Eukaryotic pathogens have complicated and dynamic genomes. To facilitate analysis of copy number variations (CNV), single nucleotide polymorphisms (SNPs), and loss of...
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  • 11

    miRStat

    identification of common sets of microRNAs for groups of genes

    miRStat enables identification of regulatory microRNA targeting several genes in a custom gene group. This Python application is based on the TargetScan 6.2 microRNA target prediction data. Conserved and Nonconserved site context+ scores files are required (unzip and place to directory with program). Available at http://targetscan.org/cgi-bin/targetscan/data_download.cgi?db=vert_61
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  • 12
    MDcons(Molecular Dynamics consensus)

    MDcons(Molecular Dynamics consensus)

    Interpretation of Biomolecular MD simulations

    MDcons is a tool to analyze conserved contacts during Molecular Dynamics (MD) simulations of Protein, Rna, Dna & Ligand based complexes. The input is either a Molecular Dynamics trajectory or a set of snapshots. The input can also be a single snapshot. The outputs are (1) map of most/less frequently conserved contacts during MD (2) a list of most/less frequently conserved contacts during MD.
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  • 13
    Spatio-temporal simulation environment (STSE) is set of tools used to perform spatio-temporal simulations, dedicated mainly to biological systems. Main development language is Python. Tools are currently based on: EPD, VTK, qhull, openalea, PlantGL.
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  • 14

    Pugsly

    Command-line, PubChem PUG client, written in Python

    Command-line, PubChem PUG client, written in Python; developed for Linux
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  • 15

    Pyntrez

    Command-line, Entrez, NCBI e-utilities client, written in Python

    Command-line, Entrez, NCBI e-utilities client, written in Python; developed for Linux
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  • 16

    Pugsly PubChem Client

    Command-line, PubChem PUG client, written in Python

    Client to the PubChem Tool (PCT), The Power User Gateway (PUG). Written in Python and developed for use with Linux.
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  • 17

    Pyntrez NCBI Database Client

    Command-line, Entrez, NCBI e-utilities client, written in Python

    Comman-line client to Entrez, e-utilities, written in Python, developed for Linux
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  • 18
    mitoMaker

    mitoMaker

    mitoMaker - a mitochondria assembly and annotation script

    mitoMaker is a pipeline script developed to simplify the assembly and automatic annotation of mitochondrial genomes, based on raw NGS reads and an optional target reference. mitoMaker calls well known assemblers and algorithms, such as SOAPdenovo, MIRA and blast+ and parses their results providing easily readable outputs, such as FASTA, GENBANK, SEQUIN, PNG and others. General pipeline: 1-iterative De Novo assembly, with different k-mer values, trying to assemble a build that matches...
    Downloads: 1 This Week
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  • 19
    Magnolya

    Magnolya

    De novo CNV detection by co-assembly

    Magnolya enables copy number variation (CNV) detections without using a reference genome. Magnolya directly compares two next-generation sequencing datasets.
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  • 20
    diCal-IBD

    diCal-IBD

    diCal-IBD predicts identical by descent tracts using sequence data

    diCal-IBD can be used for predicting identical by descent (IBD) tracts in sequence data. It provides means for calculating the accuracy of the prediction, if the true tracts are available, plotting of the predicted tracts, their TMRCA (time to the most recent common ancestor) and corresponding posterior probabilities, and identification of putative recent positive selection through investigation of average IBD sharing
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  • 21
    Pathomx

    Pathomx

    Workflow-based data analysis built on IPython

    Pathomx is a workflow-based tool for the analysis and visualisation of experimental data. Initially created as a tool for metabolomic data analysis is has been extended and can now be used for any scientific and non-scientific data analysis.
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  • 22

    xPyder PyMOL Plugin

    Analyze and visualize coupled residues and their networks in proteins

    xPyder is a PyMOL plugin to analyze and visualize on the 3D structure dynamical cross-correlation matrices (DCCM), linear mutual information (LMI), communication propensities (CP), intra- and inter-molecular interactions (e.g. PSN), and more, to produce highly customizable publication-quality images. xPyder identifies networks (using concepts from graph theory, such as hubs and shortest path searching), compares matrices and focuses the analysis on relevant information by filtering the data...
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  • 23

    mullpy

    Multilabel-learning library built on python

    Mullpy is a machine-learning library that mainly aim to solve multi-label problems. It is classifier independent, has many ensemble capabilities (diversity methods like bagging, random subspaces, etc.) and automated results presentation (Excel, images as ROC or class-separated info, etc.). It is fully configurable. At the moment supports Neural Networks and classifiers defined in files. It is working on python3.3.
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  • 24
    Protospacer

    Protospacer

    Rapid gRNA design and validation for CRISPR

    Sign up to our mailing list at http://www.protospacer.com/contact.html. Protospacer allows researchers to build, analyze, and share their own database of CRISPR target-sites. This enables the development of custom libraries and helps to transfer the CRISPR technology to new organisms. Each Protospacer database is a simple catalogue of all possible Cas9 target-sites within a given FASTA sequence, i.e. all NGG/NAG sites. Protospacer then allows the user to sub-select targets from the...
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  • 25
    IMPACT is an integrated multi-read peak calling tool for ChIP-Seq data. IMPACT utilizes multi-reads in calling peaks and provides users with high-confidence peaks. In addition, IMPACT provides a completely integrated pipeline which produces downstream analysis results such as motif discovery and peak-to-gene annotation.
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