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Structure parameter inference approach for endocrine feedback control
...It delivers the secretory capacity of pancreatic beta cells (SPINA-GBeta), an estimate for the insulin receptor amplification (SPINA-GR) and a static disposition index as a measure for the loop gain of the feedback loop (SPINA-DI).
Both implementations of SPINA have been validated in more than 50 clinical studies based on large cohorts.
Synergy analyses of drug and other other agent combinations
Combenefit software is a standalone application for Windows that performs surface analyses of drug and other agent combinations to identify synergy.
Please cite as:
"Di Veroli,G.Y. et al. (2016) Combenefit: an interactive platform for the analysis and visualization of drug combinations. Bioinformatics." (http://bioinformatics.oxfordjournals.org/content/early/2016/05/27/bioinformatics.btw230.abstract)
Current version (2.021):
https://sourceforge.net/projects/combenefit/files/Combenefit%202.02%20WIN_64%20%28PREFERRED%29/
Older version for 32-bit os:
https://sourceforge.net/projects/combenefit/files/WIN_32/
Quick user's guide:
https://sourceforge.net/projects/combenefit/files/Combenefit_v2.02_quick_guide_v1.03.pdf/download
Examples:
https://sourceforge.net/projects/combenefit/files/Examples/
Template file:
https://sourceforge.net/projects/combenefit/files/REPLICATE_TEMPLATE.xls/download