Extraction of binding sites of ligands and search for unknown binding sites on apoproteins. Some call it docking. Some call it binding site detections. Some call it knowledge based.
The Swiss Protein Identification Toolbox (swissPIT) is a project at the Swiss Institute for Bioinformatics (SIB) in Geneva which aims at the development of an automated analysis system to identify proteins using MS and MS/MS based data.
ChemCpp is a C++ toolbox for chemoinformatics focusing on the computation of kernel functions between chemical compounds. Together with Support Vector Machines, these kernel functions find natural applications for virtual screening of molecules.
PepT-IDE is a protein analysis tool that is used for multiple sequence alignment, 3D visualization and displaying protein contact maps for protein sequences and structures. It also has feedback communication between the different views of the protein.
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The goal of the GeneText project is the development of a software package that will enable users to dynamically generate an information summary page from multiple sources given a search term. Fields of interest are biology, genetics and bioinformatics.
XAS is a software with graphical user interface to performan analysis of data generated by a high-throughput expression cloning technology using gene expression microarrays.
ORFer reads the NCBI GenBank XML sequence format and extracts open reading frames for proteins. Sequences can be requested by GI or accession number. ORFprimer is an extended software package for high throughput PCR primer design for biological sequences
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PubMode is an Emacs extension that allows to search and retrieve bibliographic data from the PubMed database of biomedical literature. It is designed to integrate seamlessly with LaTeX/BibTeX in the process of creating scientific publications.
Referent Tracking (RT) is a novel approach to store data in electronic (health) records by referring to real world entities by means of a unique ID. The RT System is a back-end that uses RDF as a representation, but adds to it a referential semantics.
The Systems Biology Research Tool (SBRT) is both an application and an application programming interface (API) intended to facilitate the computational aspects of systems biology.
CLIMS is a Laboratory Information Management System for protein Crystallography that features a novel graphical interface to a relational database. CLIMS has been reviewed as one of the top two LIMS for crystallographers by CCP4.
Geneview is a visualisation tool to display genetic sequence data stored in nucleic sequence databases like <A HREF="http://www.ncbi.nlm.nih.gov/Genbank/">GenBank</A>.
GRIP is a clinical decision support system for controlling glucose levels in critically ill patients. GRIP may replace paper-based protocols for intensive insulin therapy and can use arbitrary complex rules to advise nurses on insulin doses.
EST Express is an open-source, cross-platform web server application that imports sequences from cDNA libraries and provides several layers of annotation based on Entrez Gene to allow the user to highlight useful genes and manage cDNA library projects.
The metabolomics standards initiative (msi) will develop a Core Information for Metabolomics Reporting (CIMR) recommendation and a more formal and semantically defined corresponding ontology (msi-ontology).
The ONTO-SPARQL library contains sparql-queries for loading OBO-ontologies, and for browsing and searching through them. The results of the queries are returned in XML or a HTML-interface. They can be used by end-users and programmers.