GenNon-h
Simulating non-homogeneous multiple sequence alignments
A number of software packages are available to
generate DNA MSAs evolved under
continuous-time Markov processes on phylogenetic trees. On the other hand,
methods of simulating the DNA MSA directly from the transition matrices
do not exist. Moreover, existing software restricts to
the time-reversible models and it is not optimized to
generate nonhomogeneous data (i.e. placing distinct substitution rates at different lineages).
GenNon-H is the first package designed to generate multiple...