2 projects for "optimize" with 2 filters applied:

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  • 1
    Application to optimize DNA sequences coding protein to put in in the different organizm (f.e. human protein in E.Coli). It proposes the optimal cutting places to connect many shorter fragments into bigger one using ligaze.
    Downloads: 0 This Week
    Last Update:
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  • 2

    PolyCTLDesigner

    Python scripts for designing polyepitope T-cell immunogens

    Given the peptides (T-cell epitopes) PolyCTLDesigner selects flanking sequences to optimize TAP-binding and joins resulting oligopeptides into a polyepitope in a way providing efficient liberation of potential epitopes by proteasomal and/or immunoproteasomal processing and minimizing the number of junctional epitopes. For constructing polyepitopes PolyCTLDesigner utilizes known amino acid patterns of proteasome cleavage and TAP-binding specificity.
    Downloads: 2 This Week
    Last Update:
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