Acará is an easy-to-use DVD creator for Unix* build with PyQt4
Disillusion is an audio and video converter based on AviSynth and x264 aimed toward intermediate and expert encoders. The GUI version aims to be as feature-rich as possible, focusing only on truly useful features rather than novelties and aesthetics.
Linux Multimedia Converter is a swiss-army knife for converting between different multimedia formats. It can handle image, audio and video files along with batch processing and an easy to use interface.
MediaPub is an archival-quality content repository from which an author can store, distribute, and track the use of their published digital works such as articles, presentations, photographs, ebooks, multimedia, etc.
This project is supposed to offer the ability to encode video files using an easy-to-use, intuitive, web-based interface so that you can use even non-local machines. It uses Transcode and MEncoder for encoding.
PSPy is a content manager for the Sony PSP. You will have acces to your homebrews, games backup, savegames, videos and music. Written in Python for Unix systems, using Glade/pyGTK, under the GPL license.
Shazan is an audio/video conversion tool. It's GUI for ffmpeg and other conversions softwares for linux users.
TubeJackr is a powerful, free YouTube client that allows you to search for videos and download or stream the video directly from the client. TubeJackr also has an option called FastJack which allows users to load videos without loading a new page.
The ggmpeg is a GTK+ front-end to ffmpeg. I am designing it especially for operations on many files and as much simple as I can. Still in development, not working yet, but it will soon =)