pomegranate
Fast, flexible and easy to use probabilistic modelling in Python
...The modular implementation allows one to easily drop normal distributions into a mixture model to create a Gaussian mixture model just as easily as dropping a gamma and a Poisson distribution into a mixture model to create a heterogeneous mixture. But that's not all! Because each model is treated as a probability distribution, Bayesian networks can be dropped into a mixture just as easily as a normal distribution, and hidden Markov models can be dropped into Bayes classifiers to make a classifier over sequences. Together, these two design choices enable a flexibility not seen in any other probabilistic modeling package.