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OpenFold carefully reproduces (almost) all of the features of the original open source inference code (v2.0.1). The sole exception is model ensembling, which fared poorly in DeepMind's own ablation testing and is being phased out in future DeepMind experiments. It is omitted here for the sake of reducing clutter. In cases where the Nature paper differs from the source, we always defer to the latter. OpenFold is trainable in full precision, half precision, or bfloat16 with or without DeepSpeed, and we've trained it from scratch, matching the performance of the original. ...