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...With YARA you can create descriptions of malware families (or whatever you want to describe) based on textual or binary patterns. Each description, a.k.a rule, consists of a set of strings and a boolean expression which determines its logic. YARA is multi-platform, running on Windows, Linux and Mac OS X, and can be used through its command-line interface or from your own Python scripts with the yara-python extension. YARA-CI may be a useful addition to your toolbelt. This is GitHub application that provides continuous testing for your rules, helping you to identify common mistakes and false positives. If you plan to use YARA to scan compressed files (.zip, .tar, etc) you should take a look at yextend, a very helpful extension to YARA developed and open-sourced by Bayshore Networks.

readpe (formerly known as pev) is a multiplatform toolkit to work with PE (Portable Executable) binaries. Its main goal is to provide feature-rich tools for properly analyze binaries with a strong focus on suspicious ones.

Anoubis is a Security Suite which implements a secured environment for applications. The core of the suite is an Application Firewall alongside with a Sandbox. Mechanisms to assure the authenticity of files, directories and applications are provided.