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...The system builds upon traditional structure-from-motion (SfM) techniques to provide geometric constraints while integrating a convolutional neural network trained for single-image depth estimation. During inference, the model fine-tunes itself to align with the geometric constraints of a specific input video, ensuring stable and realistic depth maps even in less-constrained regions. This approach achieves improved geometric consistency and visual stability compared to prior monocular reconstruction methods. The project can process challenging hand-held video footage, including those with moderate dynamic motion, making it practical for real-world usage.

...Some typical applications of DRAMMS include, -- Cross-subject registration of the same organ (can be brain, breast, cardiac, etc); -- Mono- and Multi-modality registration (MRI, CT, histology); -- Longitudinal registration (pediatric brain growth, cancer development, mouse brain development, etc); -- Registration under missing correspondences (e.g., vascular lesions, tumors, histological cuts). DRAMMS runs in command line in UNIX/Mac OS, It accepts Nifti/ANALYZE/MetaImage image formats. It is fully-automatic --- takes two input images, and generates a registered image and (optionally) the deformation field. More information (installation, tutorial, manual, demonstration, FAQ, etc) can be found at http://www.rad.upenn.edu/sbia/software/dramms/ .