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The AlphaGenome API provides access to AlphaGenome, Google DeepMind’s unifying model for deciphering the regulatory code within DNA sequences. This repository contains client-side code, examples, and documentation to help you use the AlphaGenome API. AlphaGenome offers multimodal predictions, encompassing diverse functional outputs such as gene expression, splicing patterns, chromatin features, and contact maps. The model analyzes DNA sequences of up to 1 million base pairs in length and can...

...The project includes code and an inference API intended to make it practical to run forecasts programmatically, with options to use different backends such as Torch or Flax depending on your environment and performance needs. Newer releases emphasize expanded context handling and more flexible forecasting outputs, including quantile forecasting so users can get uncertainty estimates rather than only point predictions. The repository also documents how model versions evolved, with newer variants focusing on efficiency and longer context windows while maintaining forecasting quality.

Biomolecular Emulator (BioEmu for short) is a model that samples from the approximated equilibrium distribution of structures for a protein monomer, given its amino acid sequence. By default, unphysical structures (steric clashes or chain discontinuities) will be filtered out, so you will typically get fewer samples in the output than requested. The difference can be very large if your protein has large disordered regions, which are very likely to produce clashes. BioEmu outputs structures in backbone frame representation. To reconstruct the side-chains, several tools are available. As an example, we interface with HPacker to conduct side-chain reconstruction and also provide basic tooling for running a short molecular dynamics (MD) equilibration.

...The project is useful for prototyping assistants, documentation bots, and internal developer tools without committing to a specific vendor or UI framework. Configuration is kept simple so newcomers can get a working chat in minutes and then dial in features like authentication or multi-model routing. While it illustrates how to hook into third-party LLM endpoints, it is typically positioned as an educational, self-hosted starter that you should operate responsibly and within provider's terms of use.