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openai-agents-python is a library developed by OpenAI to simplify the process of creating and running agents that interact with tools and APIs using OpenAI models. It provides abstractions for tool usage, memory management, and agent workflows, enabling developers to define function-calling agents that reason through multi-step tasks. Ideal for building custom AI workflows, the library supports dynamic tool definitions and contextual memory handling.

portia‑sdk‑python is an open-source Python SDK by Portia Labs for creating reliable, stateful, authenticated multi-agent AI workflows. It supports tool-backed agents capable of real-world interactions—like web browsing, API access, and human-in-the-loop clarifications—while maintaining transparency and auditability through structured plans and execution hooks. Designed for production environments, the SDK integrates with local or cloud LLMs (e.g. OpenAI, Anthropic, Mistral, Gemini) and supports extensive tool registries, session handling, and memory management.