Browse free open source Python AI Agent Frameworks and projects below. Use the toggles on the left to filter open source Python AI Agent Frameworks by OS, license, language, programming language, and project status.

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  • 1
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 19 This Week
    Last Update:
    See Project
  • 2
    Atomic Agents

    Atomic Agents

    Building AI agents, atomically

    The Atomic Agents framework is designed around the concept of atomicity to be an extremely lightweight and modular framework for building Agentic AI pipelines and applications without sacrificing developer experience and maintainability. The framework provides a set of tools and agents that can be combined to create powerful applications. It is built on top of Instructor and leverages the power of Pydantic for data and schema validation and serialization. All logic and control flows are written in Python, enabling developers to apply familiar best practices and workflows from traditional software development without compromising flexibility or clarity.
    Downloads: 14 This Week
    Last Update:
    See Project
  • 3
    CrewAI

    CrewAI

    Framework for orchestrating role-playing, autonomous AI agents

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks. The power of AI collaboration has too much to offer. CrewAI is designed to enable AI agents to assume roles, share goals, and operate in a cohesive unit - much like a well-oiled crew. Whether you're building a smart assistant platform, an automated customer service ensemble, or a multi-agent research team, CrewAI provides the backbone for sophisticated multi-agent interactions.
    Downloads: 10 This Week
    Last Update:
    See Project
  • 4
    LangGraph

    LangGraph

    Build resilient language agents as graphs

    LangGraph is a library for building stateful, multi-actor applications with LLMs, used to create agent and multi-agent workflows. Compared to other LLM frameworks, it offers these core benefits: cycles, controllability, and persistence. LangGraph allows you to define flows that involve cycles, essential for most agentic architectures, differentiating it from DAG-based solutions. As a very low-level framework, it provides fine-grained control over both the flow and state of your application, crucial for creating reliable agents. Additionally, LangGraph includes built-in persistence, enabling advanced human-in-the-loop and memory features.
    Downloads: 10 This Week
    Last Update:
    See Project
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  • 5
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 10 This Week
    Last Update:
    See Project
  • 6
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 10 This Week
    Last Update:
    See Project
  • 7
    DSPy

    DSPy

    DSPy: The framework for programming—not prompting—language models

    Developed by the Stanford NLP Group, DSPy (Declarative Self-improving Python) is a framework that enables developers to program language models through compositional Python code rather than relying solely on prompt engineering. It facilitates the construction of modular AI systems and provides algorithms for optimizing prompts and weights, enhancing the quality and reliability of language model outputs.
    Downloads: 9 This Week
    Last Update:
    See Project
  • 8
    cognee

    cognee

    Deterministic LLMs Outputs for AI Applications and AI Agents

    We build for developers who need a reliable, production-ready data layer for AI applications. Cognee implements scalable, modular data pipelines that allow for creating the LLM-enriched data layer using graph and vector stores. Cognee acts a semantic memory layer, unveiling hidden connections within your data and infusing it with your company's language and principles. This self-optimizing process ensures ultra-relevant, personalized, and contextually aware LLM retrievals. Any kind of data works; unstructured text or raw media files, PDFs, tables, presentations, JSON files, and so many more. Add small or large files, or many files at once. We map out a knowledge graph from all the facts and relationships we extract from your data. Then, we establish graph topology and connect related knowledge clusters, enabling the LLM to "understand" the data.
    Downloads: 9 This Week
    Last Update:
    See Project
  • 9
    BISHENG

    BISHENG

    BISHENG is an open LLM devops platform for next generation apps

    BISHENG is an open LLM application DevOps platform, focusing on enterprise scenarios. It has been used by a large number of industry-leading organizations and Fortune 500 companies. "Bi Sheng" was the inventor of movable type printing, which played a vital role in promoting the transmission of human knowledge. We hope that BISHENG can also provide strong support for the widespread implementation of intelligent applications. Everyone is welcome to participate.
    Downloads: 8 This Week
    Last Update:
    See Project
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  • 10
    GPTme

    GPTme

    Your agent in your terminal, equipped with local tools

    GPTMe is a personal AI chatbot designed for self-reflection, journaling, and productivity, using GPT models to generate personalized insights and responses.
    Downloads: 8 This Week
    Last Update:
    See Project
  • 11
    Open Autonomy

    Open Autonomy

    A framework for the creation of autonomous agent services

    Open Autonomy is a framework that enables the development of autonomous economic agents (AEAs) capable of operating independently in various economic contexts.
    Downloads: 8 This Week
    Last Update:
    See Project
  • 12
    Langroid

    Langroid

    Harness LLMs with Multi-Agent Programming

    Given the remarkable abilities of recent Large Language Models (LLMs), there is an unprecedented opportunity to build intelligent applications powered by this transformative technology. The top question for any enterprise is: how best to harness the power of LLMs for complex applications? For technical and practical reasons, building LLM-powered applications is not as simple as throwing a task at an LLM system and expecting it to do it. Effectively leveraging LLMs at scale requires a principled programming framework. In particular, there is often a need to maintain multiple LLM conversations, each instructed in different ways, and "responsible" for different aspects of a task.
    Downloads: 7 This Week
    Last Update:
    See Project
  • 13
    Dendrite

    Dendrite

    Tools to build web AI agents that can authenticate

    Dendrite Python SDK is a toolkit for building web AI agents that can authenticate, interact with, and extract data from any website, facilitating web automation tasks.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 14
    Haystack

    Haystack

    Haystack is an open source NLP framework to interact with your data

    Apply the latest NLP technology to your own data with the use of Haystack's pipeline architecture. Implement production-ready semantic search, question answering, summarization and document ranking for a wide range of NLP applications. Evaluate components and fine-tune models. Ask questions in natural language and find granular answers in your documents using the latest QA models with the help of Haystack pipelines. Perform semantic search and retrieve ranked documents according to meaning, not just keywords! Make use of and compare the latest pre-trained transformer-based languages models like OpenAI’s GPT-3, BERT, RoBERTa, DPR, and more. Pick any Transformer model from Hugging Face's Model Hub, experiment, find the one that works. Use Haystack NLP components on top of Elasticsearch, OpenSearch, or plain SQL. Boost search performance with Pinecone, Milvus, FAISS, or Weaviate vector databases, and dense passage retrieval.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 15
    IntentKit

    IntentKit

    An open and fair framework for everyone to build AI agents

    IntentKit is a natural language understanding (NLU) library focused on intent recognition and entity extraction, enabling developers to build conversational AI applications.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 16
    OpenAI Agents (Python)

    OpenAI Agents (Python)

    A lightweight, powerful framework for multi-agent workflows

    openai-agents-python is a library developed by OpenAI to simplify the process of creating and running agents that interact with tools and APIs using OpenAI models. It provides abstractions for tool usage, memory management, and agent workflows, enabling developers to define function-calling agents that reason through multi-step tasks. Ideal for building custom AI workflows, the library supports dynamic tool definitions and contextual memory handling.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 17
    Portia SDK Python

    Portia SDK Python

    Portia Labs Python SDK for building agentic workflows

    portia‑sdk‑python is an open-source Python SDK by Portia Labs for creating reliable, stateful, authenticated multi-agent AI workflows. It supports tool-backed agents capable of real-world interactions—like web browsing, API access, and human-in-the-loop clarifications—while maintaining transparency and auditability through structured plans and execution hooks. Designed for production environments, the SDK integrates with local or cloud LLMs (e.g. OpenAI, Anthropic, Mistral, Gemini) and supports extensive tool registries, session handling, and memory management.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 18
    magentic

    magentic

    Seamlessly integrate LLMs as Python functions

    Easily integrate Large Language Models into your Python code. Simply use the @prompt and @chatprompt decorators to create functions that return structured output from the LLM. Mix LLM queries and function calling with regular Python code to create complex logic.
    Downloads: 6 This Week
    Last Update:
    See Project
  • 19
    Agent S2

    Agent S2

    Agent S: an open agentic framework that uses computers like a human

    Simular's Agent S2 represents a leap forward in the development of computer-use agents, capable of autonomously interacting with a range of devices and interfaces. By integrating specialized AI models, Agent S2 delivers state-of-the-art performance, whether on desktop systems or smartphones. Through modular architecture, it efficiently handles complex tasks, such as navigating UIs, performing low-level actions like text selection, and executing high-level strategies like planning. Additionally, the system's proactive hierarchical planning allows for real-time adaptation, making it an ideal solution for businesses seeking to streamline operations and automate digital workflows. Agent S2 is designed with flexibility, enabling seamless scaling for future applications and tasks.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 20
    AgentUniverse

    AgentUniverse

    agentUniverse is a LLM multi-agent framework

    AgentUniverse is a multi-agent AI framework that enables coordination between multiple intelligent agents for complex task execution and automation.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 21
    Agno

    Agno

    Lightweight framework for building Agents with memory, knowledge, etc.

    Agno is a modular, open-source artificial general intelligence (AGI) research platform that allows developers to build, evaluate, and experiment with cognitive architectures in a composable way. It provides a flexible framework for modeling reasoning, memory, decision-making, and planning, aimed at long-term AI research beyond narrow learning. Agno embraces multi-agent environments and symbolic reasoning as part of its core design, enabling experiments with structured knowledge, goal-oriented behaviors, and meta-learning. It’s designed for researchers seeking an extensible platform to explore AGI components without being tied to black-box models.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 22
    DB-GPT

    DB-GPT

    Revolutionizing Database Interactions with Private LLM Technology

    DB-GPT is an experimental open-source project that uses localized GPT large models to interact with your data and environment. With this solution, you can be assured that there is no risk of data leakage, and your data is 100% private and secure.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 23
    MetaGPT

    MetaGPT

    The Multi-Agent Framework

    The Multi-Agent Framework: Given one line Requirement, return PRD, Design, Tasks, Repo. Assign different roles to GPTs to form a collaborative software entity for complex tasks. MetaGPT takes a one-line requirement as input and outputs user stories / competitive analysis/requirements/data structures / APIs / documents, etc. Internally, MetaGPT includes product managers/architects/project managers/engineers. It provides the entire process of a software company along with carefully orchestrated SOPs.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 24
    Multi-Agent Orchestrator

    Multi-Agent Orchestrator

    Flexible and powerful framework for managing multiple AI agents

    Multi-Agent Orchestrator is an AI coordination framework that enables multiple intelligent agents to work together to complete complex, multi-step workflows.
    Downloads: 5 This Week
    Last Update:
    See Project
  • 25
    Notte

    Notte

    Opensource browser using agents

    Notte is an open-source browser framework that enables the development and deployment of web-based AI agents. It introduces a perception layer that transforms web pages into structured, navigable maps described in natural language, allowing agents to interact with the internet more effectively. Notte is designed for building scalable and efficient browser-based AI applications.
    Downloads: 5 This Week
    Last Update:
    See Project
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