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MayaVi is a free, cross platform, easy to use scientific data visualizer. It provides a GUI to ease the visualization process, is written in Python and uses the Visualization Toolkit (VTK) for the graphics.
Robotic Manipulator Development and Simulation Environment in Python and Blender. IMPORTANT: Development moved to github. http://github.com/ajnsit/r2d3
LET'S 3D! (Little Easy Techniques for Simple 3D) is a library that helps developers to create 3D games/apps in a few lines of python code.It features a lightwave loader,quadtree frustum culling,movement management,improved camera class etc. Check it out
Slut is a programming framework for generative, synthetic, interactive, network-enabled graphics. THIS IS AN OLD PROJECT. But since you are interested in it you should check out the SceneExpression project: http://labs.nortd.com/sx/
Yet Another Homemade Game Engine (yahge) is what the name says a free open source 3D Game Engine geared towards development of 3D First Person Shooters. Major goals are to provide a Rapid Prototyping System for Game Ideas or to make Game Demos for Resume
Pyplace is a toolkit which helps Python developers to render data as isometrically viewed 'places' around which the user can navigate.
The look and feel by version 1 will be similar to an early UO or AOE, but only a few unit sprites & no network