Maria C. Costanzo

Show:

What's happening?

  • add synonyms to GO:0005750

    Hi, GO:0005750 : mitochondrial respiratory chain complex III currently has no synonyms, but it should have the same synonyms as its parent term GO:0045275 : respiratory chain complex III exact: complex III exact: cytochrome bc(1) complex exact: cytochrome bc1 complex exact: ubiquinol-cytochrome c oxidoreductase complex exact: ubiquinol-cytochrome-c reductase...

    2009-11-11 13:40:25 UTC in Gene Ontology

  • Open Biomedical Ontologies

    mariacostanzo committed patchset 4642 of module obo to the Open Biomedical Ontologies CVS repository, changing 1 files.

    2009-10-23 15:28:07 UTC in Open Biomedical Ontologies

  • Comment: tweaking new filamentous growth node

    Hi Jane, For 1, it would be great to just change the name and move it - I only suggested obsoletion/re-creation because I thought that was the correct procedure. It sounds fine to add the 'cell growth' parentage to 'filamentous growth of a unicellular organism'. Thanks, Maria.

    2009-10-15 13:40:59 UTC in Gene Ontology

  • Comment: tweaking new filamentous growth node

    OK, after consulting with my colleagues, I'm only requesting two changes: 1) GO:0045311 :' filamentous growth in response to pheromones' refers to a process observed in S. cerevisiae (SGD hasn't used it in annotations, but we could) and the filamentous growth involved refers to chains of single cells. So could we obsolete it and re-create it as "invasive growth in response to pheromones"...

    2009-10-15 12:27:50 UTC in Gene Ontology

  • Comment: tweaking new filamentous growth node

    I've been working on this more and I have a few more comments. 1) I think we do need to keep the general terms "regulation of filamentous growth" and the positive/negative terms. In C. albicans, some genes are involved in more than one type of filamentous growth, so it's useful to have a blanket term. 2) after submitting the original item I noticed that "hyphal growth" is a direct child...

    2009-10-13 18:16:16 UTC in Gene Ontology

  • tweaking new filamentous growth node

    Hi, I like the new terms for the different types of filamentous growth and have just a few suggestions about them. If anyone else wants to look into this, just wanted to mention that PMID: 11104818 is a nice review of fungal filamentous growth. All these suggestions are arising from the fact that since "filamentous growth" now is a parent term referring to 3 different types of filamentous...

    2009-10-13 14:48:06 UTC in Gene Ontology

  • Comment: ATP synthase protein complex biogenesis and assembly

    Maybe I'm missing something, but I don't see the need for 'protein complex biogenesis' terms. Shouldn't terms for assembly of individual protein complexes be children of biogenesis terms for the cellular component to which they belong? Maria.

    2009-09-08 15:13:05 UTC in Gene Ontology

  • Comment: new component-specific process terms?

    Hi Midori, Thanks for the reference to the email thread; I skimmed through much of it again. My take on it is the same as yours, that the consensus is that at this point we should be "fairly liberal" in creating CCxBP terms. So this is a request for the following terms: conversion of mitochondrial met-tRNAf to fmet-tRNA mitochondrial tRNA wobble uridine modification mitochondrial tRNA...

    2009-09-01 15:21:20 UTC in Gene Ontology

  • Open Biomedical Ontologies

    mariacostanzo committed patchset 4390 of module obo to the Open Biomedical Ontologies CVS repository, changing 2 files.

    2009-08-31 19:12:39 UTC in Open Biomedical Ontologies

  • new component-specific process terms?

    Hi, As I understand the discussion on component-specific process terms, it seems that we are adding them if the processes are accomplished by different gene products in the different compartments, and/or the processes are fundamentally different in some way in different compartments. Mitochondrial translation was judged to merit its own terms because the molecular machinery is evolutionarily...

    2009-08-31 18:56:29 UTC in Gene Ontology

About Me

  • 2002-09-23 (7 years ago)
  • 616548
  • mariacostanzo (My Site)
  • Maria C. Costanzo

Send me a message