I consistently get errors using the PyDev debugger with both stock Eclipse and Aptana studio, PyDev 1.4.7.x and Python 3.x. An example pulled from the error log is:
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!ENTRY org.python.pydev.debug 4 4 2009-08-17 10:53:23.854
!MESSAGE Error fetching a variable
!STACK 1
org.eclipse.core.runtime.CoreException: pydevd error:Error resolving variables...
2009-08-17 18:34:17 UTC in Pydev for Eclipse