Bioinformatics Perl extension for the analysis of antibody variable domain repertoires. Suitable for mammalian repertoire sequences obtained either by Sanger or 454 sequencing. Methods published in Glanville, Zhai, Berka et al, PNAS 2009.
- HMM-based CDR identification
- HMM-based translation and alignment
- Probabilistic germline classification
good job vdjfasta
This core module enables a variety of sophisticated antibody analysis.